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Detailed description

Indometacin Capsules product summary
Please use it under the guidance of a doctor


[drug name]
Generic name: Indometacin Capsules
English Name: Capsules Indometacin
Chinese Pinyin: Jiaonang Yinduomeixin
[character] this product is a capsule, the contents of which are white to yellowish particles and powder.
[indications]
1 arthritis, can ease the pain and swelling.
2 soft tissue injury and inflammation;
3 antipyretic;
4 others: used in the treatment of migraine, dysmenorrhea, postoperative pain, trauma, pain and so on.
[Specification] 25mg
[usage and dosage]
1 adult oral dosage:
(1) anti rheumatism, the initial dose of a 25 ~ 50mg (1 ~ 2), 2 to 3 times a day, one day the most should not exceed 150mg (6 tablets).
(2) analgesia, the first dose of a 25 ~ 50mg (1 ~ 2), following the 25mg (1 tablets), 3 times a day, until the pain relief, can be stopped.
(3) pyretolysis, a 6.25 ~ 12.5mg (1/4 ~ 1/2, grain) a day not more than 3 times.
2 pediatric oral dosage: one day by weight 1.5 ~ 2.5mg/kg, points 3 ~ 4 times. After the effective reduction to the minimum amount.
[adverse reactions]
1: gastrointestinal indigestion, stomach pain, stomach burning sensation, nausea and other symptoms of ulcers, acid reflux, stomach bleeding and perforation of stomach;
2 nervous system: the emergence of a headache, dizziness, anxiety and insomnia, etc., can be severe mental disorders or convulsions, etc.;
3 kidney: hematuria, edema, renal dysfunction, more common in the elderly;
4 different types of skin rash, the most severe bullous erythema multiforme (Stevens-Johnson syndrome),
5 the hematopoietic system was inhibited and there were aplastic anemia, white blood cells or thrombocytopenia;
6 allergic reactions, asthma, vascular edema, shock and so on.
[taboo]
Active ulcer disease, ulcerative colitis and history, epilepsy, Parkinson's disease and mental disease patients, liver and kidney function is not complete person, to the product or to aspirin or other non steroidal anti-inflammatory drug allergy, angioedema or bronchial asthma disabled.
[note] 
Cross allergic reaction: This product and aspirin have cross anaphylaxis. Asthmatic patients caused by allergy to aspirin, the application of this product can be induced bronchospasm. For other non steroidal anti-inflammatory, analgesic drug allergy may also allergic to this product.
2. The antipyretic effect, usually 1 service 6.25 mg or 12.5 mg can be quickly greatly fever. Therefore, it should be prevent profusely and collapse, adding plenty of fluids.
3 this product has inhibitory effect on platelet aggregation, which can prolong the bleeding time, and this effect can last 1 days after withdrawal, blood urea nitrogen and serum creatinine levels were also increased.
The following 4 conditions should be used with caution:
(1) this product can cause sodium retention and the cardiac insufficiency and hypertension patients should be used with caution;
(2) because of this product can make the prolonged bleeding time. Add to the bleeding tendency, so hemophilia and other bleeding disorders of patients should be used with caution, in addition, the product of the hematopoietic system is inhibited, the regeneration barrier anemia, granulocytes reduced patients should be used with caution.
5 medication should be regularly followed up for inspection:
(1) blood and liver, renal function;
(2) the case reported that this product can lead to changes in the cornea and the retina (including macular degeneration), in case of blurred vision should be immediately for eye examination.
6 in order to reduce the stimulation of the drugs on the gastrointestinal tract, this product is suitable for meals or food or antacids with clothes.
7. This product can not control the progress of the disease process, so it must be applied at the same time so as to improve the disease process can the drug. Due to the toxicity of larger, in the treatment of arthritis generally has no drug of choice, only in other non steroidal drugs are ineffective before considering application.
[pregnant women and breastfeeding women medication]
1 this product can be used in the 3 months after pregnancy, the fetal arterial catheter can be blocked, causing persistent pulmonary hypertension, pregnant women disabled.
2 this product can be discharged from the milk, the baby can cause toxic and side effects.
[children's drug use]
Children under 14 years of age are generally not suitable for the application of this drug, if necessary, should be closely observed in order to prevent the occurrence of serious adverse reactions.
Elderly patients with medication
Elderly patients are prone to renal toxicity, should be used with caution.
[drug overdose]
Dosage is too large, especially a day more than 150 mg (6 goals), easy to cause the toxic reaction, such as nausea, vomiting, tension headache, sleepiness, mental and behavior disorder, the emetic or gastric lavage, symptomatic and supportive treatment.
[storage] light shading, sealed preservation.
[packing] (1) plastic bottles, 30 grains / bottle; 100 / bottle (2) plastic packaging, 10 / box.
[valid] 24 months.
[executive standard] < Chinese Pharmacopoeia >2015 version two
[approval] Zhunzi H32020043