Ticlopidine Hydrochloride Tablets product summary

Please use it under the guidance of a doctor

[drug name]

Generic name: Ticlopidine Hydrochloride Tablets

Hydrochloride Tablets Ticlopidine

Chinese Pinyin: Sailupiding Pian Yansuan

[properties] this product is coated, after the coating was removed white or white.

Disease prevention and treatment of the heart, brain and other arteries of the heart, brain and other arteries caused by high platelet aggregation.

[Specification] 0.25g

[usage] oral administration: a time of 1 (0.25g), 1 times a day, eating to reduce the mild gastrointestinal reaction.

[adverse reactions]

1 I see a mild gastrointestinal reaction.

2. The reaction of rare: nausea, diarrhea, rashes, bruises, bleeding gums, leukopenia, cholestasis, mild amino transferase rise, mucocutaneous bleeding tendency.

3. The most common adverse reactions for lack of granulocyte (2.4%), thrombocytopenia (0.4%), gastrointestinal dysfunction and rash. The adverse reaction appeared after treatment within 3 months. I see the medication for a number of years after granulocytes reduced, thrombocytopenia and thrombosis of thrombocytopenia purpura (Thrombotic thrombocytopenic purpura, TTP) report. Severe granulocytic cells lacking TTP or even fatal. Gastrointestinal reaction more performance were nausea, vomiting and diarrhea and were generally mild, without stopping, 1 to 2 weeks after often can recover.

[taboo]

1 patients with hemophilia or other bleeding disorders, granulocyte or thrombocytopenia, ulcer disease and active bleeding patients should not use this medicine.

2 patients with severe liver damage, due to coagulation factor synthesis disorders, often increase the risk of bleeding, so this product should not be used.

3 allergic to this product.

[note]

1. To avoid surgery, Department of Stomatology and elective surgery increased amount of bleeding, preoperative 10 to 14 days should stop taking the medication. If they were in an emergency situation, transfusion of fresh platelets to help stop the bleeding. Intravenous injection of methyl prednisolone 20 mg can be bleeding time returned to normal within 2 hours.

2 patients with severe renal impairment due to decreased renal clearance, resulting in increased blood concentration, thereby increasing the damage to the kidney function, so the use of this product should monitor the renal function closely, when necessary, can be reduced.

3. During the treatment should be regularly monitored blood, initially for three months in every two weeks. Once the white blood cells or platelets decline should be discontinued and continue to monitor to return to normal.

This product is suitable for 4 meals for medication, foods can improve its bioavailability and reduce the adverse reaction of gastrointestinal tract.

5 take this product if the patient is injured and there is the risk of secondary bleeding, should be suspended to take the medicine.

6 to avoid aggravating bleeding, elective surgery (including extraction) 10 to 24 days before the withdrawal of the product.

7 in the course of medication if there is bleeding complications, blood platelets can help to stop bleeding.

[pregnant women and lactating women] this product can be through the placental barrier and into the mother's milk, should be avoided for pregnant women and lactating women.

The trial was not carried out and there was no reliable references.

The trial was not carried out and no reliable references were made.

There is no reliable reference to the test and no reliable references.

[storage] light shading, sealed preservation.

[packing] plastic packing, 6 / box.

[Effective] 30 months

[executive standard] < Chinese Pharmacopoeia >2015 version two

[approval] Zhunzi H10970289