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  • Doxycycline Hydrochloride
Detailed description

Doxycyclane Hyclate Tablets product summary

Please use it under the guidance of a doctor


[drug name]

Generic name: Doxycyclane Hyclate Tablets

Hyclate Tablets Doxycycline

Chinese Pinyin: Duoxihuansu Pian Yansuan

[character] this product is light yellow piece.

[indications]

1 this product as a selection of drugs can be used for any of the following diseases: (1) rickettsial diseases, such as endemic typhus, endemic typhus, Rocky Mountain fever, scrub typhus and Q fever. (2) mycoplasma infection. (3) Chlamydia infection, including psittacosis, venereal disease, lymph granuloma, nonspecific urethritis, oviduct is phlogistic, cervicitis and chlamydia. (4) and relapsing fever. (5) brucellosis. (6) cholera. (7) tularemia. (8) a plague. (9) soft chancre. Treatment of brucellosis and plague need combined with aminoglycosides.

2 due to the current common pathogenic bacteria of tetracycline resistance is serious, only in the pathogenic bacteria sensitive to this product, the use of indications, most of the Staphylococcus species are resistant to this drug.

3. The product can be used to penicillins allergic patients with tetanus, gas gangrene, yaws, syphilis, gonorrhea and leptospirosis and Actinomyces spp., Listeria infection.

4 can be used in moderate and severe acne patients as adjuvant therapy.

[Specification] according to 0.1g calculation C22H24N2O8

[usage and dosage]

Antibacterial and anti parasitic infection: adult, 100 mg (1) the first day, once every 12 hours, following the 100 ~ 200 mg (1 ~ 2), 1 times a day, or 50 to 100 mg (1/2 ~ 1 piece), once every 12 hours. Bacteria neisseria gonorrhea urethritis and cervicitis: 100 mg (1) at a time, once every 12 hours, a total of 7. Non neisseria gonorrhea urethritis of sex of bacterium, by chlamydia trachomatis or caused the urea urea solution, and caused by chlamydia trachomatis pure sex urethritis, cervicitis or rectal infection: is a 100 mg (1), 2 times a day, the course of at least 7. Syphilis: a 150 mg (1.5), once every 12 hours, course of treatment. At least 10 children aged 8 according to the weight of 2.2 mg/kg, the first day once every 12 hours, following by weight 2.2 ~ 4.4 mg/kg, 1 times a day, or according to the weight of 2.2 mg/kg, once every 12 hours. The pediatric dosage of more than 45 kg weight with adults.

[adverse reactions]

1. The digestive system: This product is orally can cause nausea, vomiting, abdominal pain, diarrhea and other gastrointestinal reactions. Occasionally esophagitis and esophageal ulcers reported, multiple was born in medication immediately bedridden patients.

2. Liver toxicity: fatty liver degeneration patients and pregnant women are prone to, can also occur in patients with no above. Can occur even pancreatitis, this product caused by pancreatitis can also be associated with liver toxicity occur at the same time, the patients are not associated with primary liver disease.

3. Allergic reactions: maculopapular and erythema, a small number of patients can have urticaria, angioedema, allergic purpura, pericarditis, and systemic lupus erythematosus skin lesions increased epidermal stripping off dermatitis is not common. Occasional allergic shock and asthma. Some used the product with the sun may have photosensitive phenomenon. So the product period can not be exposed to direct sunlight or ultraviolet suggested that patients who take, once the skin has erythema should be discontinued immediately.

4 blood system: I can cause hemolytic anemia, thrombocytopenia, neutrophils and eosinophils.

5 central nervous system: I can lead to increased intracranial pressure, can be manifested as headache, vomiting, optic nerve nipple edema, etc., can be relieved after withdrawal.

6 double infection: long-term use of this product can occur resistant Staphylococcus aureus, gram negative bacteria and fungi caused by the digestive tract, respiratory tract and urinary tract infection, severe cases can lead to sepsis.

7. Tetracycline application can make the human body normal flora is reduced, and caused the lack of vitamins, fungal propagules, dry mouth, pharyngitis, stomatitis and glossitis.

[taboo] there is a history of the use of tetracycline allergy banned.

[note] 

1 the use of this product may occur in the excessive reproduction of drug resistant bacteria. Once the double infection occurs, that is, the withdrawal of the product and the corresponding treatment.

2 treatment of sexually transmitted diseases, such as suspected concurrent with syphilis infection, the use of dark field microscopy examination and serological examination, the latter 1 times a month, at least 4 times.

Follow up check the blood and liver function of 3 long-term treatment.

4 patients with renal dysfunction can be applied to the product, do not have to adjust the dose, the application of this product is usually not cause blood urea nitrogen increased.

5 this product can be used with food, milk or carbonated drinks with the same service.

[Medicine] for pregnant and lactating women can enter the fetus through the placenta barrier this product, deposition in teeth and bone calcium, causing fetal tooth discoloration, enamel hypoplasia and inhibit the growth of fetal bone, this kind of drugs in animal experiments are caused by teratogenic effects, so pregnant women should not be used. This product can self milk secretion and higher concentration in milk, the application of breast-feeding women should suspend breastfeeding.

Children under 8 years of age children disabled.

The trial was not carried out and no reliable references were made.

[drug overdose] this product without a specific antagonist, drug overdose should given emetic, gastric lavage and drinking lots of fluids and fluid such as symptomatic treatment and supportive care.

[storage] light shading, sealed preservation.

[packing] plastic bottle packaging, 100 / bottle.

[Effective] 36 months

[executive standard] < Chinese Pharmacopoeia >2015 version two

[approval] Zhunzi H32020364